Publications by authors named "F Numano"
Article Synopsis
- Left ventricular noncompaction (LVNC) is a hereditary heart condition marked by unusual heart muscle structure, and this study specifically focused on biventricular noncompaction (BiVNC) in children to understand its clinical characteristics and genetic factors.
- The research involved 234 pediatric patients and revealed that BiVNC often leads to serious complications, including a higher incidence of congenital heart disease and reduced survival rates compared to other heart conditions.
- Findings indicated that patients with BiVNC frequently exhibited left ventricular dysfunction and a notable percentage had genetic variants linked to mitochondrial and developmental issues, emphasizing the need for thorough genetic screening for better patient outcomes.
Article Synopsis
- Gastroschisis is a birth condition where a baby’s organs stick out through a hole in their belly, and it can be really tough to treat, especially for tiny babies born early.
- A baby girl, born at just 29 weeks and weighing less than a kilogram, needed special surgery right after birth to help her belly hold her organs better.
- Although she faced serious health issues like infections and not gaining weight, she eventually got better and was able to go home after 142 days in the hospital.
Article Synopsis
- The study aimed to evaluate if angiotensin type 1 receptor blockers (ARBs) or ACE inhibitors (ACEis) can help reduce the size of coronary artery aneurysms (CAA) in Kawasaki disease (KD) patients.
- Conducted in Japan, the research involved 209 patients diagnosed with KD and medium to large CAAs, with a significant portion also using ARBs/ACEis.
- Although both groups had similar overall CAA regression rates, those taking ARBs/ACEis showed a higher regression rate for giant CAAs, suggesting potential benefits of these medications, especially in more severe cases.
Refractory chylothorax, a postoperative complication of CHD, is difficult to manage and sometimes fatal. Herein, we report the case of a 10-month-old infant with 22-mosaic trisomy and a coarctation complex, who developed refractory chylothorax after cardiac repairs and was successfully treated with midodrine, an oral alpha-1-adrenoreceptor agonist. Midodrine may be used as adjunctive therapy for postoperative refractory chylothorax.
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