Combination of radiofrequency and intralesional steroids in the treatment of keloids: a pilot study.

Background: None of therapeutic options for the treatment of keloids has been found completely effective and satisfactory. A combination approach is the best modality.

Objective: To assess the clinical safety and efficacy of radiofrequency (RF) followed by intralesional (IL) steroid injection in keloids.

The Pro12Ala polymorphism of the gene for peroxisome proliferator activated receptor-gamma is associated with a lower Global Acne Grading System score in patients with acne vulgaris.

Background: Acne vulgaris is a multifactorial disease of the skin. Several studies have shown that sebocyte proliferation and/or lipogenesis, as well as inflammatory reactions, may be regulated by peroxisome proliferator-activated receptor (PPAR)γ-mediated pathways.

Aim: To investigate whether the Pro12Ala polymorphism of the PPARγ gene might be associated with the risk of acne, and to assess the effect of this polymorphism on acne severity.