Publications by authors named "F Noorman"
Article Synopsis
- The study investigates the impact of platelet transfusions on mortality in trauma patients experiencing massive bleeding.
- Data collected from Dutch trauma centers showed that patients receiving a higher platelet to red blood cell (RBC) ratio had significantly lower mortality rates within 6 and 12 hours compared to those receiving lower ratios or no platelets.
- The findings suggest that higher platelet ratios, along with better plasma:RBC ratios, may lead to improved survival outcomes in these patients, though the ideal transfusion strategy is still uncertain.
Is whole blood transfusion also an option? Whole blood is gaining popularity in the treatment of traumatic massive haemorrhage. The prospective study of Hazelton et al. in 2022 shows that mortality is reduced in patients treated with whole blood and components versus the use of components only.
View Article and Find Full Text PDFWhole blood is gaining popularity in the treatment of traumatic massive haemorrhage. The prospective study of Hazelton et al. in 2022 shows that mortality is reduced in patients treated with whole blood and components versus the use of components only.
View Article and Find Full Text PDFBackground: Whole blood (WB) transfusion received renewed interest after recent armed conflicts. The effectiveness as compared with blood component transfusion (BCT) is, however, still topic of debate. Therefore, this study investigated the effect of WB ± BCT as compared with BCT transfusion on survival in trauma patients with acute hemorrhage.
View Article and Find Full Text PDFAssessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study.
Transfusion
January 2023
Background: Structural and biochemical changes in stored platelets are influenced by collection and processing methods. This international study investigates the effects of platelet (PLT) processing and storage conditions on HMGB1, sCD40L, and sCD62P protein levels in platelet concentrate supernatants (PCs).
Study Design/methods: PC supernatants (n = 3748) were collected by each international centre using identical centrifugation methods (n = 9) and tested centrally using the ELISA/Luminex platform.