Publications by authors named "F Nocera"
Background: Approximately 30% of the non-small cell lung cancer (NSCLC) patients which harbor no recognizable oncogenic driver mutation are not eligible for targeted therapy. Functional drug screening of tumor cells helps to identify susceptible drug targets not recognized by gene panels for targeted mutation analysis. The aim of this study is to characterize the BH1406 cell line carrying an activating SOS1 mutation and to check its sensitivity to cognate inhibitors.
View Article and Find Full Text PDFBackground: Ventral mesh rectopexy (laparoscopic and robotic) is a common and well established treatment of rectal prolapse. Although described as safe and effective, complications, especially mesh-associated ones are often mentioned. Additionally, there is no consensus regarding the mesh type and fixation method as well as the materials used for this purpose.
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- * ET/HT can be cautiously used after vulvar cancers, melanoma, and certain endometrial cancers, while more caution is needed with adenocarcinomas and uterine sarcomas.
- * For breast cancer survivors, ET/HT is likely safe after ER/PR-negative cancers but should be applied carefully after ER/PR-positive cases.
Herpesvirus (HV) is widely distributed among cetacean populations, with the highest prevalence reported in the Mediterranean Sea. In this study, a comprehensive analysis was conducted, including epidemiological, phylogenetic, and pathological aspects, with particular emphasis on neuropathology, to better understand the impact of HV in these animals. Our results show a higher presence of HV in males compared to females, with males exhibiting a greater number of positive tissues.
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- Monitoring stranded marine mammals helps assess their health and conservation status within marine ecosystems globally.
- This study analyzes pathogen prevalence among cetaceans stranded in Italy from 2015 to 2020, highlighting the challenges faced during post-mortem examinations due to decomposition and logistics.
- Statistical findings indicate a correlation between age and sex of the mammals and the presence of pathogens, suggesting a need for improved diagnostic frameworks for better conservation strategies.