Influence of obtaining medical records and laboratory data on the sensitivity of diagnostic imaging assessment by radiological technologists.

The purpose of this study is to clarify the influence of acquiring medical record information and laboratory data on the sensitivity of detecting imaging findings among Japanese radiological technologists (RTs). RTs were presented with patient's information in three distinct sequences for detecting imaging findings. True positives (TP) were identified and categorized into three groups: Group 1 (image + chief complaint), Group 2 (image + chief complaint + medical record), and Group 3 (image + chief complaint + medical record + laboratory data).

COMPARISON BETWEEN THE FAST STRATEGIES OF A VIRTUAL REALITY PERIMETRY AND THE HUMPHREY FIELD ANALYZER IN PATIENTS WITH GLAUCOMA.

Purpose: This study compared the agreement between the Humphrey Field Analyzer (HFA) SITA Fast strategy and a novel virtual reality head-mounted visual perimetry device (VisuALL) in glaucoma patients.

Design: This is prospective observational study.

Participants: This study was conducted on 62 eyes of 39 glaucoma subjects.

[Effectiveness of Radiological Technologists in Reporting Computed Tomography Findings in After-hour Emergencies].

Purpose: This study investigated the effectiveness of assistive work of radiological technologists (RTs) in conducting computed tomography (CT)/magnetic resonance imaging (MRI) during emergencies.

Methods: In total, 2681 examinations in 2294 patients who underwent CT or MRI during our after-hours clinic hours were conducted. The emergency of the diseases was classified into three categories: emergency diseases, semi-emergency diseases, and non-emergency diseases.

Development and structural determination of an anti-PrP aptamer that blocks pathological conformational conversion of prion protein.

Prion diseases comprise a fatal neuropathy caused by the conversion of prion protein from a cellular (PrP) to a pathological (PrP) isoform. Previously, we obtained an RNA aptamer, r(GGAGGAGGAGGA) (R12), that folds into a unique G-quadruplex. The R12 homodimer binds to a PrP molecule, inhibiting PrP-to-PrP conversion.

Defined TLR3-specific adjuvant that induces NK and CTL activation without significant cytokine production in vivo.

Ligand stimulation of the Toll-like receptors (TLRs) triggers innate immune response, cytokine production and cellular immune activation in dendritic cells. However, most TLR ligands are microbial constituents, which cause inflammation and toxicity. Toxic response could be reduced for secure immunotherapy through the use of chemically synthesized ligands with defined functions.