Publications by authors named "F Nilsson"
Aims: Nirmatrelvir/ritonavir (NMV/r) is an orally administered antiviral indicated for the outpatient treatment of adult patients with mild-to-moderate COVID-19 at high risk for disease progression to severe illness. We estimated the cost-effectiveness of NMV/r versus best supportive care for 54 patient cohorts, specified according to age, vaccination status and comorbidity burden.
Materials And Methods: A previously published and validated cost-effectiveness model was utilized and adapted to the Swedish setting.
Water-soluble polymers are materials rapidly growing in volume and in number of materials and applications. Examples include synthetic plastics such as polyacrylamide, polyacrylic acid, polyethylene glycol, polyethylene oxide and polyvinyl alcohol, with applications ranging from cosmetics and paints to water purification, pharmaceutics and food packaging. Despite their abundance, their environmental concerns (e.
View Article and Find Full Text PDFThermoplastic properties in cellulosic materials can be achieved by opening the glucose rings in cellulose and introducing new functional groups. Using molecular dynamics, we simulated amorphous cellulose and eight modified versions under dry and moist conditions. Modifications included ring openings and functionalization with hydroxy, aldehyde, hydroxylamine, and carboxyl groups.
View Article and Find Full Text PDFArticle Synopsis
- This study evaluates the effectiveness of different sunitinib dosing regimens in treating metastatic renal cell carcinoma in Sweden from 2006 to 2019.
- The analysis shows significant differences in both time-to-treatment discontinuation and overall survival among the dosing regimens, with the 2-weeks on, 1-week off schedule showing the best outcomes.
- Despite these findings suggesting that alternative dosing could enhance treatment efficacy, careful interpretation is necessary due to changing treatment patterns and lack of patient risk category data.
Article Synopsis
- Stem cell therapies for Parkinson's disease are progressing, with new clinical trials starting to test human pluripotent stem cells for creating transplantable dopamine-producing cells.
- These dopamine progenitor cells initially appear uniform but develop into a mix of different cell types after being transplanted into patients.
- Research using advanced techniques like RNA-seq has revealed that key components of these grafts, including dopamine neurons and astrocytes, originate from a single type of precursor cell that can become multiple cell types.