Publications by authors named "F Niimura"
Article Synopsis
- Researchers developed a machine learning-based software program for analyzing lung sounds in infants and children to assess airway conditions.
- The program demonstrated strong reliability and reproducibility in studies involving younger and older children, unaffected by airflow conditions.
- The findings revealed that infants with a history of wheezing or asthma showed significant differences in lung sound parameters compared to healthy infants, proving the software's potential for early asthma detection and intervention.
Article Synopsis
- The study explores how the COVID-19 pandemic affected the prevalence of respiratory infections and asthma in young children.
- It compares data from infants born during the pandemic in Japan to those born before it, focusing on asthma incidents at 18 months and 3 years of age.
- Results suggest that pandemic conditions, which limited viral infections, may have led to a lower incidence of asthma in children under 18 months, highlighting the need for infection prevention in early infancy.
Obesity is a major risk factor for end-stage kidney disease. We previously found that lysosomal dysfunction and impaired autophagic flux contribute to lipotoxicity in obesity-related kidney disease, in both humans and experimental animal models. However, the regulatory factors involved in countering renal lipotoxicity are largely unknown.
View Article and Find Full Text PDFPaired box 2 (Pax2) is a transcription factor essential for kidney development and is reactivated in proximal tubular epithelial cells (PTECs) during recovery from kidney injury. However, the role of Pax2 in this process is still unknown. Here the role of Pax2 reactivation during injury was examined in the proliferation of PTECs using an ischemia-reperfusion injury (IRI) mouse model.
View Article and Find Full Text PDF