Publications by authors named "F Nicola"

Anthropogenic pressures affect large stretches of Mediterranean coastal environments, determining alterations, including chemical pollution, able to impair ecosystem functioning and services. Among the pollutants of major concern for their toxicity and persistence, there are polycyclic aromatic hydrocarbons (PAHs), which can be effectively monitored through bioaccumulation approaches. However, the main biomonitor of PAHs in the Mediterranean Sea, Posidonia oceanica, is currently undergoing extensive regressions due to anthropogenic pressures, forcing the search for alternative biomonitors.

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Article Synopsis
  • The study analyzes bacteremia and antibiotic resistance in Gram-negative bacilli among patients with hematological malignancies and those undergoing hematopoietic stem cell transplants across different geographic regions.
  • It includes 1,277 cases of bacteremia, revealing that Gram-negative bacilli were present in 60.3% of episodes, with a notable occurrence of multidrug-resistant organisms (MDROs) affecting 40.2% of these infections.
  • Key risk factors for 30-day mortality identified include relapse of underlying disease, use of corticosteroids, and the presence of resistant bacteria, emphasizing the high mortality associated with carbapenem-resistant cases.
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The leaves of trees and shrubs can capture atmospheric pollutants such as polycyclic aromatic hydrocarbons (PAHs), and the capacity of uptake depends on the leaf traits. Although numerous studies have measured PAH concentrations in leaves of woody plants and the variability in leaf traits, few have investigated the relationship between these factors. We conducted a literature review to summarize the available information on this topic and found that five types of leaf traits have been studied, with those associated with leaf morphology and gas exchange being the most common.

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Co-localization of spatial transcriptome information of host and pathogen can revolutionize our understanding of microbial pathogenesis. Here, we aimed to demonstrate that customized bacterial probes can be successfully used to identify host-pathogen interactions in formalin-fixed-paraffin-embedded (FFPE) tissues by probe-based spatial transcriptomics technology. We analyzed the spatial gene expression of bacterial transcripts with the host transcriptomic profile in murine lung tissue chronically infected with Mycobacterium abscessus embedded in agar beads.

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