Publications by authors named "F N O'Keeffe"

Background: People with young-onset Parkinson's disease (YOPD), a term for those diagnosed with Parkinson's disease (PD) under the age of 60, face unique challenges compared to those diagnosed with PD later in life. A better understanding of the lived experience of those with YOPD is essential to delivering bespoke rehabilitation and improving quality of life.

Purpose: To provide insight into the emotional and social lived experience of individuals with YOPD.

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Background: Long COVID, described as "the continuation or development of new symptoms 3 months after the initial SARS-CoV-2 infection", is estimated to affect at least 10-20 % of all cases of acute SARS-CoV-2 infection. Because of its novelty, information regarding the experience of Long COVID is still emerging.

Methods: This study examines psychological distress in two long COVID populations, and their experience of fatigue, cognitive failures, experiential avoidance, rumination, and perceived injustice.

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Aim: Autologous haematopoietic stem cell transplant (HSCT) is an effective treatment for people with highly-active relapsing multiple sclerosis (MS), who are not adequately responding to disease-modifying therapies. To date, research has predominantly focused on disease-specific outcome measures. There is a lack of research exploring patient experiences of this complex treatment.

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Neck dystonia is a neurological condition, characterised by involuntary movements of the neck muscles, causing twisted head positions and often pain and head tremor. Ten participants with neck dystonia were interviewed and the data was analysed using an interpretative phenomenological analysis approach. Three themes were constructed: (1) dismissed by others for having an unfamiliar condition; (2) negotiating a new social identity; and (3) managing the stigma of a visible condition.

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Article Synopsis
  • - This review investigates cognitive and immune differences in individuals suffering from post-COVID syndrome, focusing on changes occurring twelve or more weeks after COVID-19 infection.
  • - Eleven studies were analyzed, revealing significant cognitive impairments, particularly in executive function, alongside increased inflammation markers in post-COVID patients compared to healthy controls.
  • - The findings suggest a link between elevated immune responses and cognitive deficits, indicating immune status may predict cognitive function after COVID-19 infection.
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