Publications by authors named "F Mouquet"
Transthyretin amyloidosis (ATTR) is a severe and rare disease characterized by the progressive deposition of misfolded transthyretin proteins, causing irreversible organ damage. Transthyretin amyloidosis can present as a hereditary ATTR or acquired wild-type ATTR form. Genetic testing is critical for determining a hereditary predisposition and subsequently initiating appropriate family screening.
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- The ECOST-CRT study assessed whether integrating a comprehensive remote monitoring (RM) scheme into heart failure (HF) care could improve patient outcomes compared to standard RM methods.
- 652 patients with cardiac resynchronization therapy (CRT) devices were split into two groups: one receiving only standard monitoring and the other receiving additional symptom tracking and notifications.
- Despite finding better quality of life improvements in the comprehensive RM group, the study did not show a significant difference in all-cause mortality or hospitalizations for worsening heart failure, partly due to early termination caused by the COVID-19 pandemic.
Article Synopsis
- The study evaluated the CardioMEMS™ HF System in 103 French patients to assess its feasibility, safety, and clinical benefits post-implantation.
- Over two years, no device-related complications were reported, and the system showed a 50% reduction in heart failure hospitalizations compared to the year before implantation.
- Additionally, patients experienced lower pulmonary artery pressures and improvements in their functional class and overall quality of life.