Publications by authors named "F Mottola"
The correlation between epigenetic alterations and the pathophysiology of human infertility is progressively being elucidated with the discovery of an increasing number of target genes that exhibit altered expression patterns linked to reproductive abnormalities. Several genes and molecules are emerging as important for the future management of human infertility. In men, microRNAs (miRNAs) like miR-34c, miR-34b, and miR-122 regulate apoptosis, sperm production, and germ cell survival, while other factors, such as miR-449 and sirtuin 1 (SIRT1), influence testicular health, oxidative stress, and mitochondrial function.
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- Exposure to the Russian-Ukrainian War led to severe mental health issues among residents from 11 countries, with Ukrainians experiencing the worst effects.
- The study identified factors like previous mental disorders and perceived stress as common predictors of PTSD and CPTSD, while some unique factors, such as gender and relationship status, also played a role.
- Findings emphasize the importance of mental health support for populations affected by ongoing conflict, especially given the uncertain threat of war in many areas.
Unlabelled: The study aimed to evaluate the biosurfactants (BSs) production by SM-23 strain of identified by phenotypical and WGS analysis as . We first demonstrated the lipopeptides production by specie and studied their biochemical and molecular analysis as well as their biological potential. The GC-MS analysis indicated that methyl.
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- Sirolimus-coated balloons (SCBs) show promise for treating de novo lesions, but there is limited long-term data available on their effectiveness and safety.
- This study analyzed outcomes from 771 patients who received SCBs, focusing on metrics like cardiac death, myocardial infarction, and revascularization, with a median follow-up of 640 days.
- Results indicated low rates of adverse events, including a 1.3% rate of cardiac death and 8% overall major adverse cardiac events (MACE), suggesting SCBs may be a viable treatment option in real-world settings.
In recent decades, industrialization, intensive agriculture, and urban development have severely impacted marine environments, compromising the health of aquatic and terrestrial organisms. Inadequate disposal results in hundreds of tons of plastic products released annually into the environment, which degrade into microplastics (MPs), posing health risks due to their ability to biomagnify and bioaccumulate. Among these, polystyrene MPs (PS-MPs) are significant pollutants in marine ecosystems, widely studied for their reproductive toxicological effects.
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