[Creatine kinase and lactate dehydrogenase in the early diagnosis of acute myocardial infarct].

The authors investigated in a group of 504 patients--357 men and 147 women with acute myocardial infarction on admission to hospital--the relationship between the ECG finding and values of catalytic concentrations of isoenzymes CK-MB and LD-1 LD-2. They found that isoenzymes CK-MB and LD-1 LD-2 are a more sensitive indicator of acute IM than the ECG tracing. Not even a negative ECG tracing when the total catalytic concentrations of CK and LD are not elevated rules out the possibility of acute myocardial infarction.

Proteinuria is a risk factor for proximal type of peripheral vascular disease in type 2 diabetic patients.

The levels of creatinine, urea, uric acid, UPE and blood pressure were measured in the groups of Type 2 diabetics with proximal (iliocofemoral) type (PRMA) and distal (tibial) type of macroangiopathy (DIMA) (diagnosed by means of Doppler ultrasound technique) and in a control group without lower limb macroangiopathy. Both UPE and creatinine mean values were significantly increased in the PRMA group in comparison with controls. Uric acid levels were increased in both PRMA and DIMA groups and mean urea values did not differ significantly in all three groups of patients.

Different levels of cardiovascular risk factors in type-2 diabetic patients with lower limb proximal and distal vessel macroangiopathy.

The levels of some cardiovascular risk factors (lipids, apolipoproteins and fibrinogen) were measured in groups of Type-2 diabetic patients with lower limb proximal (ileofemoral) and distal (trifurcational) artery macroangiopathy, diagnosed by Doppler ultrasound, and in a group of diabetics without macroangiopathy. The highest mean levels of total and LDL-cholesterol, apolipoprotein B and triacylglycerols were observed in patients with proximal vessel involvement. Significant correlations were found between the thigh/arm index and total cholesterol, LDL-cholesterol, apolipoprotein B and stroke prevalence.