Publications by authors named "F Mooi"

Article Synopsis
  • Whooping cough (pertussis) is a contagious respiratory disease caused by a bacterium, and despite high vaccination rates, it has seen a resurgence in Australia with two significant epidemics since 2007.
  • A genomic study of 385 samples from 2008 to 2017 revealed multiple co-circulating epidemic lineages, with different genetic variations expanding and contracting during the outbreaks.
  • The findings indicate that new lineages are more likely to spread locally within the first 1.5 years, and a certain allele replacement may help the bacteria evade immune detection in a highly vaccinated population.
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Purpose: The corrected carotid flow time (ccFT) is derived from a pulsed-wave Doppler signal at the common carotid artery. Several equations are currently used to calculate ccFT. Its ability to assess the intravascular volume status non-invasively has recently been investigated.

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Objective: Carotid Doppler ultrasound has been a topic of recent interest, as it may be a promising noninvasive hemodynamic monitoring tool. In this study, the relation between carotid artery blood flow and invasive cardiac output (CO) was evaluated.

Design: A prospective, observational study.

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Background: In 2013, the World Health Organization reported a shortage of 17 million red blood cell units, a number that remains growing. Acts to relieve this shortage have primarily focused on allogeneic blood collection. Nevertheless, autologous transfusion can partially alleviate the current pressure and dependence on blood banking systems.

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Bordetella pertussis vaccine escape mutants that lack expression of the pertussis antigen pertactin (Prn) have emerged in vaccinated populations in the last 10-20 years. Additionally, clinical isolates lacking another acellular pertussis (aP) vaccine component, filamentous hemagglutinin (FHA), have been found sporadically. Here, we show that both whole-cell pertussis (wP) and aP vaccines induced protection in the lungs of mice, but that the wP vaccine was more effective in nasal clearance.

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