Publications by authors named "F Mok"
To compare the effect of moderate-intensity aquatic treadmill exercise (ATM) on cerebral blood flow (CBF) and cognitive function in healthy older adults to that of moderate-intensity land-based treadmill exercise (LTM). This randomized controlled trial study was conducted between May 2023 and Oct 2023. Twenty-eight participants aged 60-80 were randomly assigned to either ATM group (N = 14) or LTM group (N = 14).
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- Interstitial lung disease (ILD) is a serious complication related to EGFR tyrosine kinase inhibitors (TKIs), particularly osimertinib, which can lead to significant drug-related mortality.
- A study of 913 NSCLC patients showed that 3.8% developed symptomatic ILD from osimertinib, with alarming rates of recurrent ILD observed upon rechallenge; specifically, 63% of those rechallenged with osimertinib experienced recurrence, compared to just 11% for erlotinib.
- Consequently, it is recommended that patients with symptomatic osimertinib-induced ILD should avoid osimertinib rechallenge, while erlotinib may be a safer alternative to consider.
This project was undertaken to develop the first set of consensus statements regarding the management of pancreatic ductal adenocarcinoma (PDAC) in Hong Kong, with the goal of providing guidance to local clinicians. A multidisciplinary panel of experts discussed issues surrounding current PDAC management and reviewed evidence gathered in the local context to propose treatment recommendations. The experts used the Delphi approach to finalise management recommendations.
View Article and Find Full Text PDFBackground: The prevalence of gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) in post-irradiated patients with nasopharyngeal carcinoma (NPC) is unknown.
Materials And Methods: In a cross-sectional study, 31 NPC and 12 control patients completed questionnaires for GERD/LPR before esophageal manometry and 24-h pH monitoring. The DeMeester score and reflux finding score (RFS) were used to define GERD and LPR, respectively.
Background: Exercise-based swallowing training (EBST) and transcutaneous neuromuscular electrical stimulation (TNMES) are common modalities used to treat late dysphagia after radiotherapy for nasopharyngeal carcinoma (NPC). We aimed to investigate and compare the efficacies of EBST and TNMES as proactive treatments administered early after radiotherapy.
Methods: Patients with early post-radiotherapy NPC ( = 120) underwent either TNMES or EBST.