Publications by authors named "F Miele"

Article Synopsis
  • - Cancer is a significant global health issue, leading to ongoing research into effective treatments, particularly focusing on natural compounds from plants that may help in prevention and therapy due to their pharmacological benefits.
  • - The review evaluates the therapeutic potential of five natural compounds—apigenin, quercetin, piperine, curcumin, and resveratrol—highlighting their anticancer mechanisms, roles in personalized cancer care, and advantages like low toxicity and compatibility with standard treatments.
  • - It emphasizes the need for innovative delivery systems and personalized approaches to enhance the effectiveness of these compounds, ultimately supporting a multidisciplinary strategy for improving cancer management and patient outcomes.
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Particle tracking (PT) is a popular technique in microscopy, microfluidics and colloidal transport studies, where image analysis is used to reconstruct trajectories from bright spots in a video. The performance of many PT algorithms has been rigorously tested for directed and Brownian motion in open media. However, PT is frequently used to track particles in porous media where complex geometries and viscous flows generate particles with high velocity variability over time.

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Background: Supportive Care is a person-centred approach encompassing non-pharmacological interventions targeted towards persons with dementia to contain the effects of their behavioural disorders, improving their quality of life.

Aims: To investigate the effects of lockdown restrictions during the first wave of COVID-19 pandemic on behavioural symptoms of patients involved in a Supportive Care programme in an Italian nursing home.

Methods: Analysis is based on Neuropsychiatric Inventory (NPI) scores and related symptoms data collected before (October/November 2019) and after (July 2020) the introduction of COVID-19 restrictions on a non-random sample of 75 patients living in two units of the facility: 38 involved in a Supportive Care programme and 37 receiving standard care (Control).

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Article Synopsis
  • Robotic surgery allows for precise tissue control but often leads to significant drops in hemoglobin (Hb) levels after procedures like robot-assisted radical prostatectomy (RARP) for prostate cancer.
  • A study analyzed Hb changes and potential predictive factors in 110 patients who underwent RARP, finding a notable Hb drop from a median of 14.6 g/dl pre-surgery to 12.7 g/dl by postoperative day one, with stabilization occurring shortly afterward.
  • Multivariable analyses showed that factors like age, BMI, and intraoperative variables did not significantly predict the extent of Hb drop, suggesting that other management strategies may be important for postoperative care.
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Background: Insomnia persists as a prevalent sleep disorder among middle-aged and older adults, significantly impacting quality of life and increasing susceptibility to age-related diseases. It is classified into objective insomnia (O-IN) and paradoxical insomnia (P-IN), where subjective and objective sleep assessments diverge. Current treatment regimens for both patient groups yield unsatisfactory outcomes.

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