Electrophysiological studies of the interaction between ventricular myocardium and coronary artery in monkeys.

1. The electrical influence of the coronary arteries on ventricular muscle was investigated using strips of ventricle that included a section of coronary artery (cardiac preparation) and isolated coronary arteries dissected from the ventricle (arterial preparation). 2.

Endothelium-dependent contraction produced by acetylcholine and relaxation produced by histamine in monkey basilar arteries.

The present experiments were carried out to investigate the endothelium dependence of the responses to acetylcholine (ACh), arachidonic acid, and histamine in monkey basilar arteries. ACh and arachidonic acid caused endothelium-dependent contraction (EC) in both monkey and canine basilar arteries. The endothelium-derived contracting factor (EDCF) was probably thromboxane A2 (TxA2), as the EDC was attenuated by a cyclooxygenase inhibitor, TxA2 synthetase inhibitors, and TxA2 antagonists.

Electrical responses of coronary artery smooth muscle associated with the cardiac muscle action potential in the monkey.

1. In cardiac strips of the monkey ventricle which included a section of coronary artery (cardiac preparation), a depolarizing response, which appeared to be an excitatory junction potential (EJP), and a hyperpolarizing response were observed from the coronary artery smooth muscles when an action potential was generated in cardiac muscle by the application of electrical stimulation to the cardiac muscle alone. 2.

The role of hyperpolarization in the relaxation of smooth muscle of monkey coronary artery.

In monkey coronary arteries, outer and inner muscle had a similar resting potential (-39.5 and -40.0 mV).

Different electrical responses of outer and inner muscle of rabbit carotid artery to noradrenaline and nerves.

Electrical responses of outer and inner muscle of the rabbit carotid artery to electrical stimulation and noradrenaline were investigated. Mean values of the resting potential and space constant in the direction of the long axis of the cells were -47.3 mV and 1.