Publications by authors named "F Mehendale"

Article Synopsis
  • Inclusivity in research is vital for capturing diverse opinions, especially from experienced healthcare workers, whose insights can significantly influence future research directions.
  • The study adapted the Child Health and Nutrition Research Initiative (CHNRI) methodology to incorporate various stakeholders—including research experts, clinicians, patients, and NGOs—across the globe in setting research priorities for orofacial clefts.
  • Despite receiving 412 responses and extensive input from multiple specialties, the study faced challenges like underrepresentation of patient inputs and language management, highlighting the need for ongoing efforts to enhance inclusivity in research prioritization.
View Article and Find Full Text PDF

Background: "Clean Cleft" (CC) is an adaptation of the Lifebox Clean Cut program, designed to reduce surgical site infections (SSIs) in cleft lip and palate repairs. It focuses on 6 key processes: hand and site decontamination, surgical linen integrity, instrument sterility, timely antibiotic use, gauze counting, and WHO Surgical Safety Checklist compliance. The study explores CC's effectiveness in reducing infections, other complications, and enhancing early recovery.

View Article and Find Full Text PDF

Objective: There is currently no consensus about managing upper airway obstruction (UAO) in infants with Robin sequence (RS), in terms of treatment efficacy or clinical outcomes. This study describes UAO management in UK/Ireland, and explores relationships between patient characteristics, UAO management, and clinical outcomes in the first 2 years of life.

Methods: Active surveillance of RS throughout UK/Ireland via the British Paediatric Surveillance Unit and nationally commissioned cleft services.

View Article and Find Full Text PDF

Background: Among infants with isolated cleft palate, whether primary surgery at 6 months of age is more beneficial than surgery at 12 months of age with respect to speech outcomes, hearing outcomes, dentofacial development, and safety is unknown.

Methods: We randomly assigned infants with nonsyndromic isolated cleft palate, in a 1:1 ratio, to undergo standardized primary surgery at 6 months of age (6-month group) or at 12 months of age (12-month group) for closure of the cleft. Standardized assessments of quality-checked video and audio recordings at 1, 3, and 5 years of age were performed independently by speech and language therapists who were unaware of the trial-group assignments.

View Article and Find Full Text PDF