Publications by authors named "F Medioli"
Objective: People with HIV (PWH) have high risk of liver fibrosis. We investigated the effect of weight gain and metabolic dysfunction-associated steatotic liver disease (MASLD) on liver fibrosis dynamics.
Design: Multicenter cohort study.
Background: Intravenous drug users (IDUs) have a high risk of developing skin and soft tissue infections such as erysipelas, abscesses, and less frequently necrotizing fasciitis (NF) or gas gangrene. Rarely, the cause of the infection is microorganisms residing in the oral cavity and can lead to life-threatening infections.
Methods: We describe the case of a 43-year-old man intravenous drug user (IDU) who was admitted for intense leg pain following an injection of cocaine at that site.
Article Synopsis
- * A specific challenging case of S. maltophilia BSI due to septic thrombosis is presented, where the infection was successfully treated using cefiderocol in addition to levofloxacin.
- * The treatment plan also included an intra-lock therapy with trimethoprim/sulfamethoxazole to prevent reinfection, as full resolution of the infection source was not achievable, supported by a serum bactericidal assay to confirm the treatment's effectiveness.
Article Synopsis
- Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a significant threat in healthcare settings, with over a 40% mortality rate among critically ill patients; this review focuses on the best infection prevention and control (IPC) strategies to combat its spread in hospitals.
- A critical review of literature from the past 10 years assessed IPC measures in various settings, with the majority of studies centered on ICU outbreaks, showing high mortality rates up to 50%.
- The review found that while some IPC measures like environmental disinfection were universally applied, others varied significantly by study and setting, emphasizing that targeted 'search and destroy' strategies are key to effective CRAB control.