Anti-inflammatory medication adherence and cost and utilization of asthma care in a commercially insured population.

Objective: The authors hypothesized that adherence to anti-inflammatory treatment could reduce overall cost of asthma care, as higher spending on drugs would be offset by reductions in hospital and emergency care.

Methods: A retrospective observational study using 2 years of claims data for 41,234 commercially insured asthmatics on monotherapy with either leukotriene inhibitors (LI) or inhaled corticosteriods (ICS). Patients were grouped into adherence quartiles based on the percentage of days per year they had prescriptions filled (medication possession ratio).

Quality of care for childhood asthma: estimating impact and implications.

We conducted a review of 164 relevant publications to consolidate the evidence on gaps in the quality of asthma care, the impact of those gaps, and the costs and benefits of closing those gaps. Researchers used a wide variety of definitions for measures of quality asthma care, clinical and utilization end points, and disease severity. Gaps in care were most evident for pharmacologic treatment, particularly the underuse of inhaled corticosteroids, with median usage rates of 40%; however, in studies with large proportions of black subjects, the inhaled corticosteroid usage rate was only 32%, compared with 51% for nonminority populations.

Laser welding of NiTi orthodontic archwires for selective force application.

Conventional superelastic orthodontic wires are arch-shaped, have the same mechanical properties all along their length and are used to correct the position of teeth. The disadvantage of these archwires is that there are different types of teeth in the mouth and different forces are therefore needed to rectify their position. The aim of this work was to laser weld several types of NiTi orthodontic wires that had different chemical compositions and superelastic properties, in order to adjust their properties to different parts of the mouth.