Cognitive Distortions and Decision-Making in Women Victims of Intimate Partner Violence: A Scoping Review.

Exposing women to intimate partner violence (IPV) poses a risk to their physical and mental health, necessitating that they leave the relationship. However, women face various obstacles in doing so, such as cognitive distortions that affect their interpretation of the reality of violence, trapping them and significantly influencing their decision to leave. This scoping review explores, synthesizes, and analyzes the available evidence on the relationship between cognitive distortions and decision-making among women involved in IPV.

EEG headbands vs caps: How many electrodes do I need to detect emotions? The case of the MUSE headband.

Background: In the realm of emotion detection, comfort and portability play crucial roles in enhancing user experiences. However, few works study the reduction in the number of electrodes used to detect emotions, and none of them compare the location of these electrodes with a commercial low-cost headband.

Methods: This work explores the potential of wearable EEG devices, specifically the Muse S headband, for emotion classification in terms of valence and arousal.

Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer.

Despite the established use of immune checkpoint inhibitors (ICIs) to treat non-small cell lung cancer (NSCLC), only a subset of patients benefit from treatment and ∼50% of patients whose tumors respond eventually develop acquired resistance (AR). To identify novel drivers of AR, we generated murine Msh2 knock-out (KO) lung tumors that initially responded but eventually developed AR to anti-PD-1, alone or in combination with anti-CTLA-4. Resistant tumors harbored decreased infiltrating T cells and reduced cancer cell-intrinsic MHC-I and MHC-II levels, yet remained responsive to IFNγ.

G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1.

The treatment of non-small cell lung cancer (NSCLC) patients has significantly improved with recent therapeutic strategies; however, many patients still do not benefit from them. As a result, new treatment approaches are urgently needed. In this study, we evaluated the antitumor efficacy of co-targeting G9a and DNMT1 enzymes and its potential as a cancer drug sensitizer.