Publications by authors named "F Marrazzo"

Article Synopsis
  • Researchers investigated the effects of breathing hypoxic gas (oxygen levels < 0.21) in 5 healthy volunteers over 5 days to assess safety and physiologic changes.
  • Subjects spent time in a hypoxic tent, gradually decreasing oxygen levels to as low as 0.11, with their oxygen saturation, heart rate, and other health metrics continuously monitored.
  • Findings indicated significant physiologic changes with no adverse effects, suggesting that low oxygen levels can be safely tested in hospital settings, paving the way for future studies on the therapeutic benefits of hypoxia.
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Breastfeeding is a fundamental biological function in mammals, allowing the progeny to develop in a physiological way. A physical and emotional dialog between mothers and offspring during breastfeeding has been described as part of the attachment relationship, and a synchronicity between maternal and neonatal brains can be hypothesized. This study aimed to assess if neonatal and maternal cortical areas activated during breastfeeding are functionally synchronized since the second day of life.

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In this case report, we present the experience of a premature neonate born at 28 weeks of gestation who, following prolonged respiratory support, developed a pressure injury on the columella despite the implementation of all appropriate preventive techniques. This injury did not improve with standard therapies; therefore, it was necessary to apply a topical galenic therapy containing epidermal growth factor, resulting in complete healing of the lesion.

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Background: The use of prone position (PP) has been widespread during the COVID-19 pandemic. Whereas it has demonstrated benefits, including improved oxygenation and lung aeration, the factors influencing the response in terms of gas exchange to PP remain unclear. In particular, the association between baseline quantitative computed tomography (CT) scan results and gas exchange response to PP in invasively ventilated subjects with COVID-19 ARDS is unknown.

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