Publications by authors named "F Maltais"
Trends in COPD severe exacerbations, and all-cause and respiratory mortality, before and after implementation of newer long-acting bronchodilators in a large population-based cohort.
BMC Pulm Med
September 2024
Background: Little is known about the trends in morbidity and mortality at the population level that followed the introduction of newer once-daily long-acting bronchodilators for COPD. The purpose of the study was to evaluate whether the availability of new bronchodilators was associated with changes in the temporal trends in severe COPD exacerbations and mortality between 2007 and 2018 in the older population with COPD; and whether this association was homogeneous across sex and socioeconomic status classes.
Methods: We used an interrupted time-series and three segments multivariate autoregressive models to evaluate the adjusted changes in slopes (i.
Background: The most near-term clinical application of genome-wide association studies in lung cancer is a polygenic risk score (PRS).
Methods: A case-control dataset was generated consisting of 4002 lung cancer cases from the LORD project and 20,010 ethnically matched controls from CARTaGENE. A genome-wide PRS including >1.
Article Synopsis
- Pulmonary rehabilitation is essential for individuals with chronic lung diseases, but access to these services is limited, particularly during the COVID-19 pandemic, making telerehabilitation a valuable option.
- The study focuses on validating the 6-minute stepper test (6MST) as a home-friendly alternative to traditional exercise tests like the maximal cardiopulmonary exercise test (CPET) and the 6-minute walk test (6MWT).
- Researchers will assess 6MST’s validity and reliability through a multinational study with 30 participants, collecting data on its correlation with CPET and 6MWT, as well as monitoring experiences during home-based testing.
Background: Cardiovascular comorbidities are increasingly being recognised in early stages of chronic obstructive pulmonary disease (COPD) yet complete cardiorespiratory functional assessments of individuals with mild COPD or presenting with COPD risk factors are lacking. This paper reports on the effectiveness of the cardiocirculatory-limb muscles oxygen delivery and utilisation axis in smokers exhibiting no, or mild to moderate degrees of airflow obstruction using standardised cardiopulmonary exercise testing (CPET).
Methods: Post-bronchodilator spirometry was used to classify participants as 'ever smokers without' (n=88), with 'mild' (n=63) or 'mild-moderate' COPD (n=56).