Publications by authors named "F Madhani"

Background: Clinical breast exam (CBE) by outreach healthcare workers (HCW) may help downstage breast cancer in resource-limited areas where mammography may not be feasible. We evaluated the effectiveness of a pilot cascade-model training programme for HCWs in remote areas of Pakistan.

Methods: The training programme comprised three phases.

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Article Synopsis
  • Pakistan has one of the highest rates of tuberculosis (TB) in the world, and a study was conducted to assess the prevalence of TB in adults and the risk of M. tuberculosis infection in children in Karachi, focusing on areas with and without prior active case-finding (ACF) activities.
  • The research involved surveys between March 2018 and May 2019, with almost 35,000 adults and over 1,500 children participating, revealing a higher prevalence of TB in areas with no prior ACF (421 cases per 100,000) compared to areas with prior ACF (279 cases per 100,000).
  • The findings indicated that ACF efforts in Korangi district likely reduced TB prevalence and transmission,
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Pakistan has among the highest rates of maternal, perinatal, and neonatal mortality globally. Many of these deaths are potentially preventable with low-cost, scalable interventions delivered through community-based health worker programs to the most remote communities. We conducted a cross-sectional survey of 10,264 households during the baseline phase of a cluster randomized controlled trial (cRCT) in Gilgit-Baltistan, Pakistan from June-August 2021.

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Background: Ongoing high neonatal mortality rates (NMRs) represent a global challenge. In 2021, of the 5 million deaths reported worldwide for children under five years of age, 47% were newborns. Pakistan has one of the five highest national NMRs in the world, with an estimated 39 neonatal deaths per 1,000 live births.

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Background: Scaling up a shorter preventive regimen such as weekly isoniazid and rifapentine (3HP) for 3 months is a priority for tuberculosis (TB) preventive treatment (TPT). However, there are limited data on 3HP acceptability and completion from high-burden-TB countries.

Methods: We scaled up 3HP from 2018 to 2021 in 2 cities in Pakistan.

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