The effect of an anti-malarial herbal remedy, Maytenus senegalensis, on electrocardiograms of healthy Tanzanian volunteers.

Background: The emergence of resistance to artemisinin-based combination therapy necessitates the search for new, more potent antiplasmodial compounds, including herbal remedies. The whole extract of Maytenus senegalensis has been scientifically investigated for potential biological activities both in vitro and in vivo, demonstrating strong antimalarial activity. However, there is a lack of data on the electrocardiographic effects of M.

Safety and Tolerability of an Antimalarial Herbal Remedy in Healthy Volunteers: An Open-Label, Single-Arm, Dose-Escalation Study on in Tanzania.

Background: Though is one of the medicinal plants widely used in traditional medicine to treat infectious and inflammatory diseases in Africa, there is a lack of safety data regarding its use. Therefore, the study aimed to asselss the safety and tolerability of the antimalarial herbal remedy .

Material And Methods: The study design was an open-label, single-arm, dose-escalation.

Anti-Newcastle Disease Virus activity of 3β and 3α Friedelanol Triterpenoids from the leaves of Synadenium glaucescens Pax.

Newcastle Disease (ND) is a highly pathogenic disease of avian species which is caused by Newcastle Disease Virus (NDV). It is one of the major causes of mortality and morbidity to poultry industry in the third world countries. Currently, there is no treatment measures against ND; the only existing measure is vaccination, though it is incapable to offer 100% immunity.

Safety evaluation and bioassay-guided isolation of antimycobacterial compounds from Morella salicifolia root ethanolic extract.

Ethnopharmacological Relevance: Although the available medicines can cure almost all tuberculosis drug-susceptible patients some problems including the emergence of multi-drug resistant and extensively drug-resistant strains press for the need of new anti-TB medicines. Morella salicifolia is a common plant that is widely used in traditional medicine for managing HIV and AIDS-related conditions including tuberculosis but no studies have been done to evaluate its safety and efficacy.

Aim Of The Study: This study was designed to investigate the antimycobacterial activity and safety of M.

Two mosquito larvicidal arabinofuranosidetridecanol from exudate.

Two new arabinofuranosidetridecanol, namely 1,2-tridecanediol-1--α-L-5'-acetylarabinofuranoside () and 1,2-tridecanediol-1--α-L-arabinofuranoside () together with known compound, 1,2-tridecanediol () were isolated from exudate. Compound showed larvicidal activity against (LC = 40.66 µg/mL) (LC = 22.