Introduction: Assessment of BIA-ALCL prevalence is challenged by a lack of population-level data for the prevalence of breast implants in the wider population. Absence of such data obscures the true prevalence of BIA-ALCL and hinders informed consent consultations. We performed a systematic review to synthesise data from published studies reporting BIA-ALCL cases in defined patient populations to better inform the evidence base.
View Article and Find Full Text PDFBreast cancer (BC) is the most common female cancer, and as bilateral breast augmentation (BBA) increases, more women are presenting with BC within an augmented breast. No international guidelines exist on how to manage such a situation, so this group undertook a global survey to provide a snapshot of current surgical practice. The key finding was the variable oncoplastic management of BC after BBA: most surgeons responded that when oncologically safe, breast conservation with implant preservation was appropriate as radiotherapy was not a contra-indication to preserving implants.
View Article and Find Full Text PDFThe cognitive ecology of pollination is most often studied using simple rewards, yet flowers often contain multiple types of chemically complex rewards, each varying along multiple dimensions of quality. In this review we highlight ways in which reward complexity can impact pollinator cognition, demonstrating the need to consider ecologically realistic rewards to fully understand plant-pollinator interactions. We show that pollinators' reward preferences can be modulated by reward chemistry and the collection of multiple reward types.
View Article and Find Full Text PDFModern neoadjuvant systemic therapy (NST) can result in high pathologic complete response rates (pCR) in triple negative (TN) and human epidermal growth factor receptor 2 positive (HER2+) breast cancer. The role of surgery is, therefore, being reconsidered in this rapidly evolving field. This report presents oncological outcomes of seven patients with TN or HER2+ breast cancer, with exceptional response to NST, and a post-NST image-guided vacuum assisted biopsy showing no residual disease (ypT0), who opted not to have breast surgery.
View Article and Find Full Text PDFMod Pathol
December 2023