Publications by authors named "F MAGNAN"
Study Question: How do oocyte donors and recipients perceive the genetic link related to the transfer of nuclear DNA between donors and offspring?
Summary Answer: Whether they are donors or recipients, individuals attach great importance to the transmission of their genetic heritage, since 94.5% would opt for the pronuclear transfer method to preserve this genetic link in the context of oocyte donation.
What Is Known Already: Since 1983, the use of oocyte donation has increased worldwide.
Purpose: To assess the value of having an onsite genetic counseling service integrated into an assisted reproductive technology (ART) center.
Methods: Since January 2021, we have offered genetic counseling at our ART center for couples whose medical history suggests risk of transmission of a genetic disorder. The percentage of couples referred for genetic counseling, the distribution of couples according to reasons for consultation, the mode of transmission in cases of Mendelian disorders, and the frequency of mutations for those with identified genetic disorders were determined.
Most of transgender people plan to have a family but their fertility may be affected by gender affirmation. Hormone therapy can permanently affect gamete production, especially in trans women. Sex reassignment surgery leads to permanent sterility.
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- Many transgender individuals have high reproductive desires, but fertility preservation and sperm donation options in France were limited until recently due to restrictive Bioethics Law.
- A national survey conducted at 28 reproductive technology centers revealed that a significant number of these centers provide services for fertility preservation, with 71.4% treating transgender patients.
- Results indicated that transgender women are more likely to seek and achieve fertility preservation compared to transgender men, and a notable percentage of centers offer sperm donation services for couples including transgender men.
A hexaazatrinaphtylene-based transition metal complex that exhibits single molecule magnet (SMM) behaviour is reported herein. Both monometallic (1) and bimetallic (2) CoII complexes with distorted octahedral geometries could be obtained through a straightforward change in synthetic conditions. Field induced SMM behaviour was exhibited by 1, with a D value of -60 cm-1 and Ueff = 17 K originating from the unquenched orbital angular momentum of the octahedral CoII (d7) centre.
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