Publications by authors named "F M Morel"
Article Synopsis
- A vaccine works best when it triggers the immune system to fight off germs. Different ingredients called adjuvants help boost this immune response.
- Scientists tested a new type of liposome (a tiny bubble) combined with special molecules to see how well it helps the immune system recognize a specific bacteria, Staphylococcus aureus.
- The results showed that this new mix could help create strong immune defenses in mice, making it a good candidate for future vaccines against tricky germs.
Dermatology
December 2023
Article Synopsis
- The study investigates the link between sebaceous neoplasms (SNs) and Muir-Torre syndrome (MTS), aiming to find the best methods for early detection of associated internal cancers.
- It involves 107 patients and employs immunohistochemistry (IHC) and molecular biology techniques to assess the presence of deficient mismatch repair (dMMR) in these tumors, alongside calculating a Mayo Clinic risk score for MTS.
- Findings suggest that using the Mayo Clinic risk score as a first step, followed by IHC testing, offers the most effective and cost-efficient approach to screen for MTS in patients with SNs.
Article Synopsis
- * The study focuses on two specific NUDIX proteins, NUDT6 and NUDT9, both found to localize to mitochondria and are confirmed to be expressed in human cells.
- * NUDT6- and NUDT9-deficiencies lead to increased mitochondrial respiratory chain activity and changes in the expression of respiratory chain complexes; they also exhibit distinct substrate specificities, with N
