Publications by authors named "F M Majidi"
Background: The coexistence of pheochromocytoma and hyperaldosteronism is a rare and clinically significant finding with diagnostic challenges that need to be considered in the workup of patients with hypertension.
Case Presentation: This case report describes a 47-year-old Iranian man who initially presented with cold symptoms, chills, and headaches. Despite being diagnosed with panic disorder, his symptoms worsened, leading to a systolic blood pressure crisis.
In a system biology-based study, we previously reported that IL-6 and IL6R -specific m-RNA levels were elevated in leukocytes of patients with Rheumatoid arthritis (RA). Here, the association of toll-like receptor4 (TLR4) rs 141534085 and cytochrome P450 family 51 subfamily A member 1(CYP51A1) rs6 with tumor necrosis factor-α (TNF- α), rheumatoid factor (RF)- and Anti- cyclic citrullinated peptide (anti-CCP) antibody -positivity was investigated in almost the same subjects. Forty-six patients and 48 normal subjects were recruited in this study.
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- The systematic review and meta-analysis assessed the impact of spiritually based interventions, like meditation and yoga, on lowering blood pressure in adults, analyzing studies published until January 2022.
- Out of 24 included studies, the results showed a significant reduction in both systolic blood pressure (SBP) and diastolic blood pressure (DBP) after these interventions, with a weighted mean difference of -7.63 for SBP and -4.75 for DBP.
- High variability among the studies was noted, but overall, the findings suggest that these spiritual practices can effectively decrease blood pressure and potentially lower cardiovascular disease risks.
Background: The effects of ginseng on fatigue have been proven in patients with multiple sclerosis (MS), which have several similar manifestations to neuromyelitis optica spectrum disorder (NMOSD) patients. This study was designed to evaluate the effects of ginseng on fatigue in NMOSD patients.
Methods: In this double-blinded randomized controlled clinical trial, 64 patients were recruited and were allocated into two study groups (ginseng or placebo) via block randomization.
Article Synopsis
- A phase 3 clinical trial (IMerge) showed positive results for imetelstat, a telomerase inhibitor, in treating transfusion-dependent patients with lower-risk myelodysplastic syndromes (MDS) who did not respond to other treatments.
- This treatment specifically targets patients who have relapsed or are refractory to erythropoiesis-stimulating agents.
- If approved, imetelstat could significantly expand the limited treatment options currently available for MDS patients.