Publications by authors named "F M Lemoine"
The Bayesian Phylogenetic Bootstrap and its Application to Short Trees and Branches.
Mol Biol Evol
November 2024
Felsenstein's bootstrap is the most commonly used method to measure branch support in phylogenetics. Current sequencing technologies can result in massive sampling of taxa (e.g.
View Article and Find Full Text PDFProblem: Research has suggested a link between recurrent pregnancy loss (RPL) and cell-mediated immunity dysregulation. We aimed to determine if a history of RPL is associated with diagnosis of a cell-mediated autoimmune condition (AIC).
Method Of Study: A retrospective cohort study was conducted using the TriNetX research network.
Article Synopsis
- A study conducted in France during the 2023-24 RSV season analyzed the effectiveness of nirsevimab, a monoclonal antibody, in preventing RSV infections in infants, focusing on breakthrough cases.
- Out of 695 RSV-infected infants, researchers sequenced the full-length RSV genome of 545 infants, identifying that 48% had breakthrough infections despite receiving nirsevimab.
- While no resistance was found in RSV-A infections from nirsevimab-treated infants, two cases of RSV-B showed substitutions linked to resistance, indicating a potential concern for the antibody's effectiveness against this variant.
Article Synopsis
- - First-generation monoclonal antibodies (mAbs) for COVID-19 were withdrawn due to resistance from Omicron variants, but two new mAbs, VYD222/Pemivibart and AZD3152/Sipavibart, were approved in 2024.
- - Researchers tested these mAbs against contemporary JN.1 sublineages and found VYD222 still had moderate activity, but AZD3152 lost effectiveness against several variants.
- - The study underscores the importance of monitoring VYD222's clinical performance and raises concerns about AZD3152's efficacy in treating infections from newer variants.
Purpose: This study aimed (1) to determine the degree of correlation between 2D and 3D estimated fetal weight (EFW) and neonatal birth weight (BW) among borderline small fetuses and (2) to compare the accuracy and precision of 2D and 3D EFW in BW prediction.
Methods: A retrospective cohort study evaluated fetuses who had an ultrasound performed between January 2017 and September 2021 at a tertiary maternal center. All singleton pregnancies with 3D EFW within 4 weeks of delivery were included.