Publications by authors named "F M Caballero"
Asymmetric fluctuations and self-folding of active interfaces.
Proc Natl Acad Sci U S A
December 2024
Article Synopsis
- The study analyzes how a boundary between a passive fluid and an active fluid made of microtubules behaves, especially under turbulence-like conditions.
- It finds that strong active flows cause the boundary to have pronounced asymmetries and local vortices, which disrupts spatial symmetry and leads to significant fluctuations at the interface.
- As the activity level increases, the interface deforms more dramatically, eventually folding in on itself and creating a foam-like structure with passive droplets embedded within the active fluid.
Background: The effect of metabolic surgery on long-term diabetes remission in Asian patients with a body mass index (BMI) < 30 kg/m has not been widely reported.
Methods: We conducted a systematic review of the PubMed and Cochrane Library databases from inception to June 2024. All clinical trials and observational studies involving the effect of metabolic surgery in Asian patients with type 2 diabetes mellitus and BMI <30 kg/m were considered.
Comparison of staging using [Ga]Ga-PSMA-11 PET/CT and histopathological results in intermediate- and high-risk prostate cancer patients treated with radical prostatectomy and pelvic lymph node dissection.
Rev Esp Med Nucl Imagen Mol (Engl Ed)
October 2024
Objective: To evaluate the diagnostic accuracy of [Ga]Ga-PSMA-11 PET/CT (PET-PSMA) in local and loco-regional nodal staging compared with histopathological results in intermediate- and high-risk prostate cancer patients treated with radical prostatectomy (RP) and pelvic lymph node dissection (PLND).
Materials Y Methods: A total of 122 intermediate- and high-risk prostate cancer (PCa) patients staged with PET-PSMA and treated with RP (36/122) and RP plus PLND (86/122) from December 2018 to December 2023 were included. Visual and semiquantitative analysis findings using the SUVmax of the molecular imaging were correlated with histopathological results.
Abstract: The tumor suppressor protein p53, a transcription factor playing a key role in cancer prevention, interacts with DNA as its primary means of determining cell fate in the event of DNA damage. When it becomes mutated, it opens damaged cells to the possibility of reproducing unchecked, which can lead to formation of cancerous tumors. Despite its critical role, therapies at the molecular level to restore p53 native function remain elusive, due to its complex nature.
View Article and Find Full Text PDFActive liquid crystals exert nonequilibrium stresses on their surroundings through constant consumption of energy, giving rise to dynamical steady states not present in equilibrium. The paradigmatic example of an active liquid crystal is a suspension of microtubule bundles powered by kinesin motor proteins, which exhibits self-sustained spatiotemporal chaotic flows. This system has been modelled using continuum theories that couple the microtubule orientation to active flows.
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