Relationships among DNA Index, S-Phase, and invasive behavior in anterior pituitary adenomas. A cytometric study of 61 cases with Feulgen-positive DNA analysis.

Background: Pituitary adenomas are usually well differentiated neoplasms, although in about 1/3 of cases they invade the surrounding dura mater and bone, as confirmed by surgical findings, resulting in a long-term possibility of relapse.

Methods: To identify the cellular growth rate and to correlate it with surgical evidence of invasiveness, we performed the analysis of DNA with static cytometric quantitation on fresh surgical specimens, using a computer-assisted image processor. The DNA index and the percentage of cells in S-phase (%SPh) were obtained in 61 pituitary tumors consecutively operated on.

[Primary cutaneous mucormycosis. A case report].

One case of primary cutaneous mucormycosis developed in the hospital environment is reported. Dressings contaminated by hyphae may have been the cause. In diabetic or immunodepressed patients this disease may be fatal.

Diabetic mastopathy. A report of two cases diagnosed by aspiration cytology.

Background: Diabetic mastopathy (DM) is a lymphocytic mastitis that develops in women who have suffered from insulin-dependent diabetes mellitus for some years.

Cases: A 51-year-old female with type 1 insulin-dependent diabetes for 13 years presented with a 3-cm, hard, mobile nodule in the right breast. A 59-year-old female on insulin therapy for five years presented with a 4-cm mass in the subareolar region of the breast.