Publications by authors named "F M Arafa"
Toxoplasmosis remains a challenge for both public health and animal husbandry which created a constant demand to develop novel compounds using innovative methods. To join this relentless quest for an ideal chemotherapeutic agent, herein, we developed newly synthesized isatin-1,2,3-triazole derivatives. Three compounds (5a, 5b and 5c) were synthesized, characterized, loaded on chitosan nanoparticles (CNPs) and then evaluated accordingly.
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- - The study investigates how type 2 diabetes mellitus (T2DM) affects the prevalence of interstitial lung disease (ILD) in patients with systemic lupus erythematosus (SLE), aiming to clarify their relationship.
- - Using data from the 2019-2020 National Inpatient Sample, researchers found that patients with SLE and T2DM had a lower prevalence of ILD compared to those without T2DM, particularly noting a reduced occurrence of pulmonary fibrosis.
- - The findings suggest that T2DM may offer some protective effects against ILD in SLE patients, and the study calls for more research into the mechanisms behind this association for improved management strategies.
Background: The impact of type 2 diabetes mellitus (T2DM) on acute respiratory distress syndrome (ARDS) is debatable. T2DM was suspected to reduce the risk and complications of ARDS. However, during coronavirus disease 2019 (COVID-19), T2DM predisposed patients to ARDS, especially those who were on insulin at home.
View Article and Find Full Text PDFLarge cell neuroendocrine carcinoma (LCNEC) constitutes a rare subset of highly undifferentiated malignancies known for their aggressive nature. Although these tumors commonly originate in the lungs and gastrointestinal tract, their potential occurrence is not restricted to specific anatomical sites, giving rise to a variety of symptoms. Notably, cases of neuroendocrine tumors (NETs) with an unidentified primary source exhibit a graver prognosis and shorter survival periods compared to those with clearly identified origins.
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- * A 93-year-old woman with a known clival chondroma showed altered mental status, which was initially thought to be caused by an infection-related brain issue.
- * Further tests showed her pituitary hormone levels were low, indicating panhypopituitarism (a condition where the pituitary gland doesn't produce enough hormones), linked to the chondroma's growth spreading toward the sellar region, highlighting the complications in diagnosis and treatment.