Publications by authors named "F M Aarestrup"
The recent expansion of mpox in Africa is characterized by a dramatic increase in zoonotic transmission (clade Ia) and the emergence of a new clade Ib that is transmitted from human-to-human (H2H) by close contact. Clade Ia does not pose a threat in areas without zoonotic reservoir. But clade Ib may spread widely, as did the clade IIb that since 2022 has spread globally among MSM.
View Article and Find Full Text PDFArticle Synopsis
- The study examines glycopeptide resistance in Copenhagen's Lynetten sewer system, which has had a consistently high level of resistance for over 20 years, focusing on the mapping of various resistance genes and their relationships with bacterial taxa.
- Analysis of genomic data showed that only limited glycopeptide resistance genes were differentially abundant, and resistance remained confined mainly to specific bacterial taxa, mainly related to the phylum Bacillota.
- The research indicates that while advanced technologies like Hi-C are useful for linking antimicrobial resistance genes to specific bacteria, they struggle with accurately mapping those genes, leading to the conclusion that resistance has not spread widely among diverse bacterial communities within the sewer.
Article Synopsis
- * The ST5477 isolates demonstrate enhanced growth and faster milk acidification, indicating better lactose utilization, which may aid their adaptation to the bovine udder environment.
- * Genetic analysis reveals that ST5477 has modifications in the lac gene region compared to the reference strain, suggesting these changes may contribute to its success as a bovine-adapted clone.
We describe cases with monkeypox virus (MPXV) Clade Ib in Burundi from their first detection in July until 20 August 2024. Testing 442 people with vesicular lesions confirmed 170 cases (98 male; 72 female), 82 (48%) being < 15 years old. Differential diagnosis of the first 30 individuals testing MPXV negative revealed chickenpox in 20.
View Article and Find Full Text PDF