Publications by authors named "F Lundberg"

Background: The possibility of future parenthood is a highly relevant issue for patients of reproductive age facing oncologic treatment. This study aimed to investigate how fatherhood was achieved in a patient cohort of adolescents and young adults (AYAs) banking semen at time of cancer diagnosis and to determine the effectiveness of cryopreservation aimed at fertility preservation in the cohort.

Materials And Methods: Observational cohort study examining AYAs with a cancer diagnosis who underwent semen banking for fertility preservation at Karolinska University Hospital 1988-2020, as part of the Stockholm regional fertility preservation program.

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Article Synopsis
  • The study evaluated the feasibility of fertility preservation (FP) in women with cervix cancer, focusing on long-term reproductive outcomes and overall survival.
  • Conducted at Karolinska University Hospital from 1999 to 2021, it included 91 women, primarily diagnosed at an early cancer stage, with various treatment options offered.
  • After an average of 8.1 years of follow-up, only a small percentage of women achieved live births, highlighting the difficulties and complexities of fertility preservation in this cancer context.
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To investigate the quality of emergency-collected semen samples aimed at sperm cryopreservation provided by adolescents and young adults (AYAs) presenting with cancer or nonmalignant diseases. This is a prospective cohort study of postpubertal males referred for sperm cryopreservation who provided at least one semen sample for fertility preservation at the Reproductive Medicine Clinic of Karolinska University Hospital, Stockholm, Sweden, between January 2009 and January 2020. Sperm quality was assessed by total sperm count, concentration, and motility.

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Article Synopsis
  • The study aimed to assess if improvements in lung cancer survival from 1990 to 2016 were consistent across different age groups and cancer types in Nordic countries.
  • Data from Denmark, Finland, Iceland, Norway, and Sweden was analyzed, showing continuous improvements in both 1- and 5-year relative survival rates for lung cancer across all demographics and subtypes, with Denmark seeing the most significant improvements.
  • Despite these advancements, lung cancer survival rates are still low, with around 75% of patients dying within five years of diagnosis.
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Study Question: What are the obstetric and perinatal outcomes in births to breast cancer survivors compared to women without previous breast cancer?

Summary Answer: Women who conceived during the first 2 years following a breast cancer diagnosis had a higher risk for preterm birth, induced delivery, and cesarean section, while no increased risks were observed in births conceived later than 2 years after a breast cancer diagnosis.

What Is Known Already: A recent meta-analysis found higher risks of cesarean section, preterm birth, low birthweight, and small for gestational age in pregnancies among breast cancer survivors. Less is known about rarer outcomes such as pre-eclampsia or congenital malformations.

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