Publications by authors named "F Lorenzoni"
Article Synopsis
- Congenital Cytomegalovirus (cCMV) is linked to serious long-term issues like hearing, vision, and neurodevelopmental problems, but there’s no standard approach for screening and treatment.
- This study reviewed data from newborns identified through targeted hearing screening, focusing on the long-term effects and any neurological abnormalities associated with cCMV over at least two years.
- Out of 61 newborns studied, 57.3% were symptomatic at birth, with a significant number developing sensorineural hearing loss, often accompanied by other complications, highlighting the need for effective monitoring and treatment strategies.
The endemic chub (Heckel, 1843) was introduced more than 100 years ago to Lake Blidinje (Bosnia-Herzegovina). Only 1 species of enteric helminth was found in a sample of 35 chubs, the tapeworm (Janiszewska, 1953). The paper includes histopathological investigation with identification of innate immune cells involved in host reaction and molecular data allowed correct designation of the cestode species.
View Article and Find Full Text PDFBackground: Congenital cytomegalovirus (cCMV) infection is the leading cause of non-hereditary sensorineural hearing loss in children. While about 10% of children reportedly display symptoms at birth, 85-90% of cCMV infection cases are asymptomatic. However, 10-15% of these asymptomatic infants may later develop hearing, visual, or neurodevelopmental impairments.
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- Environmental stressors during pregnancy, such as pollutants and metals, can affect DNA methylation, influencing the risk of chronic diseases later in life.
- The study investigated how these exposures relate to DNA methylation in placental, maternal, and neonatal cells by analyzing 28 mother-infant pairs and utilizing artificial neural networks.
- Results indicated that factors like suboptimal birth weight and maternal stress during pregnancy are linked to specific DNA methylation changes, suggesting that maternal exposure to environmental toxins can have significant implications for fetal development and health.*
In a newborn with very precocious liver failure, cholestatic jaundice, and low γ-glutamyl transpeptidase, progressive hepatosplenomegaly induced a progressively worsening respiratory distress, that was successfully treated with steroids. Laboratory and genetic tests did not find any disease usually associated with neonatal cholestasis. However, the patient was positive for a homozygous mutation of the gene, which is associated with hereditary hemochromatosis, a disease with typical onset in adulthood.
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