Publications by authors named "F Lombi"

Introduction: Given the vulnerability of chronic kidney disease individuals to SARS-CoV-2, nephrology societies have issued statements calling for prioritization of these patients for vaccination. It is not yet known whether COVID-19 vaccines grant the same high level of protection in patients with kidney disease compared to the non-dialysis population. The aims of this study were to evaluate the safety - measured by the adverse events potentially attributed to vaccines (ESAVI) - and the effectiveness - evaluated by the presence of antibodies - in dialysis patients immunized with the COVID-19 Sputnik V vaccine.

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Central venous disease (CVD) is a serious complication in hemodialysis patients. Neurological manifestations are rare. We describe a female with end-stage renal disease with throbbing headache accompanied by paresthesia, weakness, and abnormal posture of her right hand during dialysis sessions.

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Article Synopsis
  • - The Argentine Registry of COVID in chronic dialysis reported data from April 2020 to April 2021, registering 36,918 patients on dialysis, with 10% (3,709) confirmed COVID-19 cases.
  • - Of those infected, 45.2% were hospitalized, with 39% requiring ICU care, and 62% of ICU patients needing mechanical ventilation; the overall death rate was 35.24%.
  • - Factors linked to higher mortality in dialysis patients included age over 60, diabetes, extended dialysis duration, and the necessity for hospitalization or ICU admission, indicating a critical need for focused care and vaccination strategies in this high-risk group.
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In the last few years the general results in the treatment of acute kidney injury has improved constantly, without a complete comprehension of its pathophysiology. With this paradigm in mind, in these last few years we have seen an evolving comprehension of the possible answers that may be based on recognizing the more proactive role of fluid management in the resuscitation of critical patients, not limited only to the delivery of fluids, but also to their active removal, having as the principal objective the improvement of tissue perfusion. The key role of vascular integrity in fluid overload is discussed, emphasizing the role of the endothelial glycocalyx.

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