Publications by authors named "F Loko"

Article Synopsis
  • Hepatic diseases pose a significant public health challenge, and traditional herbal treatments are commonly used in Benin for conditions like hepatitis, often without scientific evaluation.
  • The study assessed the hepatoprotective properties and toxicity of 10 herbal recipes by testing different plant varieties and their proportions in treated Wistar rats.
  • Findings indicated that the herbal recipes showed no acute toxicity and that their hepatoprotective effects increased with higher doses, with wild plant varieties performing better than cultivated ones, particularly when combined with certain other plants.
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Medicinal plants such as are increasingly used for their purgative virtues to treat stomach aches, fever, and jaundice. This study aims to screen the phytochemical compounds and to assess the antioxidant activity and the acute oral toxicity of leaves. The plant was harvested, dried, pulverized, and preserved.

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Article Synopsis
  • - The study focuses on vulvovaginal candidiasis (VVC), a common infection linked to imbalances in vaginal health, aiming to assess its prevalence and related factors among women at Mènontin Hospital from March to August 2020.
  • - Data were gathered from 1,336 women's medical records, revealing a 56.25% prevalence of candidiasis among those with discharge, with no links found to age, marital status, or BMI, but connections were established with gestational age and characteristics of the discharge.
  • - Eight Candida species were identified as causing VVC, predominantly Candida dubliniensis and Candida albicans, highlighting the need for targeted control strategies based on the associated factors.
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Background: Candidiasis, an opportunistic cosmopolitan disease is nowadays like bacterial infections which is a real public health problem. In view of the emergence of Candida strains resistant to existing antifungal agents, alternative solutions should be considered. This is the purpose of this ethnobotanical survey, which aims to identify the medicinal plant species traditionally used to treat candidiasis in traditional markets of southern Benin.

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We report two outbreaks of Lassa fever that occurred in Benin in 2014 and 2016 with 20 confirmed cases and 50% (10/20) mortality. Benin was not previously considered to be an endemic country for Lassa fever, resulting in a delay to diagnose the disease and its human transmission. Molecular investigations showed the viral genomes to be similar to that of the Togo strain, which is genetically very different from other known strains and confirms the existence of a new lineage.

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