Publications by authors named "F Lieutier-Colas"
Background: GPs are responsible for more than 70% of outpatient antibiotic prescriptions in France. Metrics are important antibiotic stewardship tools that can be used to set targets for improvement and to give feedback to professionals and stakeholders.
Objectives: The primary objective of the present study was to select a set of proxy indicators (PIs) based on 10 previously developed PIs, to estimate the appropriateness of antibiotic prescriptions by GPs.
Antibiotic consumption in French nursing homes between 2018 and 2022: A multicenter survey.
Infect Control Hosp Epidemiol
June 2024
Article Synopsis
- The study monitored antibiotic consumption in 220 French nursing homes over five years, focusing on changes during the COVID-19 pandemic to improve antimicrobial stewardship.
- Findings showed a significant decrease in antibiotic use from 2018 to 2022, particularly during the pandemic, although there was a slight increase in 2022.
- The data revealed that penicillins were the most commonly used antibiotics, raising concerns about the reliance on broad-spectrum antibiotics and highlighting the need for continuous monitoring and improvement in antibiotic prescribing practices.
Antibiotic-resistant bacteria have become one of humankind's major challenges, as testified by the UN's Call to Action on Antimicrobial Resistance in 2021. Our knowledge of the underlying processes of antibiotic resistance is steadily improving. Beyond the inappropriate use of antimicrobials in human medicine, other causes have been identified, raising ethical issues and requiring an approach to the problem from a "One Health" perspective.
View Article and Find Full Text PDFThe development of broad-spectrum antibiotics to control multidrug-resistant bacteria is an outdated business model. This strategy has led to the introduction of highly effective antibiotics, but their widespread use has contributed to the emergence of even broader antibiotic resistance. In a strategy to combat antimicrobial resistance, we believe that the use of narrow-spectrum antibiotics should be promoted.
View Article and Find Full Text PDFObjectives: The aim of this study was to investigate the epidemiology of candidemia, the fungal susceptibility, the first-line therapy and the morality rate over 5 years. Knowing the differences of the yeasts in the candidemia local epidemiology, is essential to obtain information on fungal epidemiology to adapt antifungal strategies.
Materials/methods: This retrospective study was conducted from January 2014 to December 2018.