Bendiocarbamate toxicity in the chick embryo.

Carbamate pesticides generally possess low toxicity for warm-blooded vertebrates, but developmental data are scarce. We have therefore evaluated embryotoxicity of choline esterase inhibitor bendiocarbamate in the chick embryo. The pesticide was dissolved in 5% acetone in distilled water and a volume of 200 microl was administered over the embryo through membrana papyracea on embryonic days 2, 3, 4, 5, and 10.

Bendiocarb effect on liver and central nervous system in the chick embryo.

The aim of the study was to investigate toxicity of bendiocarb (2, 3-isopropyledene-dioxyphenyl methylcarbamate) to organs of chicken embryo. The toxic action of bendiocarb was observed on liver and central nervous system (CNS). Bendiocarb was administered to chicken embryos at embryonic day (ED) 3 in a dose 500 microg/egg and 10 ED (800 microg/egg).

[Host immune response in mammals to Encephalitozoon cuniculi infection].

The immunity system status of an individual plays the key role in regulation of opportune infection. In the fight against the intracellular parasites several non-specific as well as specific immunity mechanisms are applied. The dominant role in response to infection caused by the representatives of genus Encephalitozoon plays the cell-mediated immune response.

Immune response in mice infected by Encephalitozoon cuniculi and suppressed by dexamethasone.

Several indicators of immune response were observed in immunocompetent mice of the ICR line and those suppressed by dexamethasone upon their experimental infection with the microsporidia of Encephalitozoon cuniculi. The mice were infected by one-shot intraperitoneal administration of 5 x 10(7) pathogenic spores. On Days 7, 14, 28 and 42 after infection, peripheral blood leukocyte phagocytic activity was determined and compared, including phagocytic index and the blastogenic response in spleen cells to mitogenic activation by concanavalin A and phytohaemagglutinin.

An unusual manifestation of encephalitozoonosis in chinchilla rabbits.

This disease occurred in 6 rabbits in which leukemic changes after infection with the bovine leukemia virus were being studied.