Publications by authors named "F Le Boulaire"

Article Synopsis
  • The study assessed the performance of the Access anti-HBc Total assay on the DxI 9000 system, involving samples from blood donors and patients to evaluate diagnostic accuracy.
  • The assay showed a clinical specificity of 99.58% for blood donors and 99.27% for hospitalized patients, meaning it accurately identified negatives in nearly all cases.
  • Additionally, the Access assay demonstrated high sensitivity at 99.78% for positive samples and detected seroconversion earlier than a comparator assay by approximately 1.4 days.
View Article and Find Full Text PDF

Introduction: This study evaluated the clinical and analytical performances of the Access HBsAg and the Access HBsAg Confirmatory assays on the DxI 9000 Access Immunoassay Analyzer (Beckman Coulter, Inc.).

Materials And Methods: Diagnostic specificity and sensitivity of the Access HBsAg and Access HBsAg Confirmatory assays were evaluated by comparing the Access assays to the final HBsAg sample status determined using the Architect, PRISM, or Elecsys HBsAg assays, along with Architect or PRISM HBsAg Confirmatory assays.

View Article and Find Full Text PDF

The reliability of renewable hydrogen supply for off-take applications is critical to the future sustainable energy economy. Integrated water electrolysis can be deployed at distributed municipal wastewater treatment plants (WWTP), creating opportunity for reduction in carbon emissions through direct and indirect use of the electrolysis output. A novel energy shifting process where the co-produced oxygen is compressed and stored to enhance the utilisation of intermittent renewable electricity is analysed.

View Article and Find Full Text PDF

While the use of environmental factors in the analysis and prediction of failures of buried reticulation pipes in cold environments has been the focus of extensive work, the same cannot be said for failures occurring on pipes in other (non-freezing) environments. A novel analysis of pipe failures in such an environment is the subject of this paper. An exploratory statistical analysis was undertaken, identifying a peak in failure rates during mid to late summer.

View Article and Find Full Text PDF

Despite the great popularity and potential of microarrays, their use for research and clinical applications is still hampered by lengthy and costly design and optimization processes, mainly because the technology relies on the end point measurement of hybridization. Thus, the ability to monitor many hybridization events on a standard microarray slide in real time would greatly expand the use and benefit of this technology, as it would give access to better prediction of probe performance and improved optimization of hybridization parameters. Although real-time hybridization and thermal denaturation measurements have been reported, a complete walk-away system compatible with the standard format of microarrays is still unavailable.

View Article and Find Full Text PDF