Publications by authors named "F Laubscher"
Anelloviruses are ubiquitous in humans and represent a major component of the human virome. Its best-known representative is Torque teno virus (i.e.
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- * Dengue antigen rapid diagnostic tests (Ag-RDTs) are effective alternatives to traditional PCR methods for diagnosing infections, allowing for off-site testing with high sensitivity and specificity.
- * This study demonstrates the feasibility of sequencing dengue virus genomes from Ag-RDTs, even after 31 days at room temperature, enabling comprehensive genomic surveillance without the need for cold storage.
Anelloviruses are extremely prevalent in the human population and are considered to be commensal parts of the human virome. The best-known member in humans is the Torque teno virus. Recent metagenomic next-generation sequencing investigations have helped reveal the considerable number of species and genotypes from the same genus that can be co-detected within a single individual and that this diversity increases as a function of age during the first months/years of life.
View Article and Find Full Text PDFGenome sequences from evolving infectious pathogens allow quantification of case introductions and local transmission dynamics. We sequenced 11,357 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from Switzerland in 2020-the sixth largest effort globally. Using a representative subset of these data, we estimated viral introductions to Switzerland and their persistence over the course of 2020.
View Article and Find Full Text PDFObjectives: To report a prospective epidemiological, virological and serological investigation of a SARS-CoV-2 outbreak in a primary school.
Methods: As part of a longitudinal, prospective, school-based surveillance study, this investigation involved repeated testing of 73 pupils, 9 teachers, 13 non-teaching staff and 26 household members of participants who tested positive, with rapid antigen tests and/or RT-PCR (Day 0-2 and Day 5-7), serologies on dried capillary blood samples (Day 0-2 and Day 30), contact tracing interviews and SARS-CoV-2 whole genome sequencing.
Results: We identified 20 children (aged 4 to 6 years from 4 school classes), 2 teachers and a total of 4 household members who were infected by the Alpha variant during this outbreak.