Publications by authors named "F Lanyi"

Objective: Data were analyzed to assess the value of stereotactically applied intracystic colloidal yttrium-90 (YTx) for the treatment of recurrent cystic craniopharyngiomas during a 30-year period.

Methods: This article compares data from 73 YTx procedures in 60 patients between 1975 and 2006. The cumulative beta dose aimed at the inner surface of the cyst wall was 300 Gy.

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Article Synopsis
  • The study assessed the effectiveness of using intracavitary irradiation with yttrium-90 (90Y) for treating cystic craniopharyngiomas over a nearly 30-year follow-up period.
  • About 79% average reduction in cyst size was found, with 29 out of 47 cysts completely disappearing within a year, suggesting a strong treatment success.
  • Neuroophthalmological outcomes were generally favorable if the optic disc was normal at treatment; otherwise, any existing visual damage was irreversible, highlighting the importance of the patient's condition at the time of treatment.
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The authors analyzed long-term follow-up data to assess the value of intracavitary irradiation with stereotactically implanted beta-emitting radioisotope (90)Y-silicate colloid for the treatment of craniopharyngiomas. Fifty-seven craniopharyngiomas in 42 patients were selected for retrospective analysis. The yttrium-90 was implanted intracavitally, using computerized tomography-guided and three-dimensional stereotactic treatment planning.

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The authors present a case of a patient with the syndrome of paradoxical worsening of dural-sinus cavernous arteriovenous malformation which was a iatrogenic consequence of embolization of the basal branches of a dural shunt with Yvalon. It is presumed that the thrombogenous Yvalon reached the basal branches of the medial meningeal artery to the superior ophthalmic vein, where it caused complete thrombosis. The impaired ocular and orbital venous outflow caused a dramatic worsening of the ocular congestive symptoms: venous stasis retinopathy with dilated veins, flame-and dot-shaped hemorrhages and a secondary increase in intraocular pressure.

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