Obesity and colorectal cancer.

Background: To correlate obesity and colorectal cancer for Greek living conditions.

Patients And Methods: We studied 97 patients, who over the last 5 years were diagnosed histopathologically with colorectal cancer. 75.

Adjuvant chemotherapy in colorectal cancer.

Unlabelled: Our aim was to study the three-fold response to treatment, survival rates and toxicity.

Materials And Methods: We review 76 patients (median age 66.2 years) affected with the disease.

alpha-Interferon therapy in patients with chronic active hepatitis B: immunological profile.

The effect of interferon-alpha 2b (IFN) on viral markers, liver function and immunological parameters (CD3, CD4, CD8, B, NK, II-2 receptor and HLA-DR positive cells in blood and T cell proliferation) was studied in 9 patients with HBsAg(+), HBeAg(-) chronic active hepatitis (CAH). Three patients were HBV-DNA(+) and 6 also had complications of cirrhosis of the liver (LC). IFN was given at a dose of 2.

Possible mechanisms underlying peripheral lymphocyte activation in chronic liver disease and asymptomatic HBsAg carriers.

Proportions of T lymphocyte subsets (OKT3, OKT4, OKT8) and expression of interleukin-2 (IL-2), transferrin (TFR) receptors and HLA-DR antigens were studied in the peripheral blood of 21 healthy HBsAg carriers, 10 patients with chronic active hepatitis B (CAH), 10 patients with alcoholic liver cirrhosis (ALC) and 10 subjects with negative markers of previous hepatitis B virus (HBV) infection. T lymphocyte subsets ranged within normal levels in CAH and carriers, whereas a significant decrease of OKT4 was noted in ALC possibly involved in the pathogenesis of this disorder. Significantly elevated numbers of activated cells (cells expressing IL-2, TFR receptors and HLA-DR antigens) were observed in all three groups.