Tissue analysis by vibrational spectroscopy in Hirschsprung disease: feasibility and potential as a new intraoperative tool.

Hirschsprung disease is a congenital anomaly characterised by an absence of innervation in the colon. The current diagnosis, which involves identifying the non-functional part of the colon through histological examination, is unsatisfactory. The objective of our study was to assess the potential of infrared spectroscopy as a label-free method to distinguish between functional and non-functional parts of the colon.

Case reports of large and symptomatic abdominal tumors in newborns: Pitfalls, difficulties in management, and surgical decision making.

Background: Large and rapidly growing abdominal tumors may result in fatal outcomes in newborns. In some cases, a rapidly worsening clinical condition requires surgical decision-making despite the absence of a precise histological diagnosis. In these situations, there is neither a guide nor consensus.