Effect of fruit pulp powder on antioxidant and proinflammatory genes in non-diabetic and type 2 diabetic rats.

Background: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia resulting from insulin deficiency or dysfunction. The imbalance between free radicals and antioxidants known as oxidative stress has been implicated in the pathogenesis and complications associated with DM. is a seasonal fruit found to be rich in natural antioxidants.

Effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension-in vivo.

The effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension in vivo were determined. Feeding with supplemented diet with pulp reduced heart rate, mean arterial pressure, systolic and diastolic blood pressure levels of hypertensive-treated groups. Moreover, hypertensive-treated groups fed with fruit pulp supplemented diets had significantly (p < 0.

Anti-hypercholesterolemic potential of diet supplemented with and tubers in high cholesterol fed rats.

Background: One significant ethnomedicinal motivation behind Pleurotus tuberregium (PTT) and Anchomanes difformis (ADT) tubers is cardiovascular-related conditions treatment. This investigation is in this way planned for deciding the impact of PTT and ADT enhanced eating routine on key enzymes linked with hypercholesterolemia in elevated cholesterol fed rodents.

Methods: Rats were isolated into control group, hypercholesterolemic-prompted untreated group, hypercholesterolemic-treated groups with dietary routine containing PTT (5% and 10%), ADT (5% and 10%), 5% PTT and 5% ADT conbination and traditional medication, atorvastatin for 28 days.

Starch composition, glycemic indices, antioxidant properties and carbohydrate hydrolyzing enzymes activities of African star apple fruit parts.

Background: African star apple (Chrysophyllum albidum) is a traditonal fruit, which is predominant in tropical regions with the fruit parts consumed by the populace and used in folklore to manage diabetes. However, the likely activity mechanism is still undetermined. The current study examined and compared the inhibitory abilities of African star apple fruit parts on selected key enzymes related to diabetes mellitus in the pancreas tissue of rat.

Effect of dietary inclusion of pumpkin (Cucurbita pepo L) seed on nephrotoxicity occasioned by cisplatin in experimental rats.

The study evaluated the effect of dietary inclusion of pumpkin (Cucurbita pepo L) seed (raw and roasted) on nephrotoxicity caused by cisplatin in rats. Rats were divided into control group, cisplatin-induced nephrotoxic untreated group, nephrotoxic-treated groups with Methimazole, dietary regimen containing raw pumpkin seed (5% and 10%) and roasted pumpkin seed (5% and 10%) for 14 days. Results acquired uncovered that cisplatin intoxication significantly increased (p ≤ .