Improved positioning in robotic assisted laparoscopic partial nephrectomy using the EDGE MP1000 surgical robot.

This study investigated the impact of an improved body positioning on the effectiveness of EDGE MP1000 robot-assisted laparoscopic partial nephrectomy. We compared clinical data from 39 patients who underwent the procedure at Zhujiang Hospital of Southern Medical University between November 2023 and May 2024. The control group (18 patients) received conventional positioning, while the experimental group (21 patients) received precise positioning, which included patient assessments, optimized positioning techniques, and enhanced nursing measures.

Effect of metformin on the clinical outcomes of stroke in patients with diabetes: a systematic review and meta-analysis.

Objectives: Stroke is a major cause of death and disability globally, especially among diabetic patients. In this study, we aim to scrutinise the effects of metformin on the clinical outcomes of stroke in diabetic patients.

Design: This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Comparing residual kidney function equations based on β2-microglobulin in Chinese patients undergoing continuous ambulatory peritoneal dialysis.

Background: Few studies have evaluated the predictive capability of equations for residual kidney function (RKF) in patients undergoing peritoneal dialysis (PD). Moreover, the applicability of each equation remains unclear. Therefore, we aimed to evaluate the performances of the estimated RKF (eRKF) equations of Shafi, Steubl, and Jaques in Chinese patients undergoing continuous ambulatory peritoneal dialysis (CAPD).

Customized Design of Covalent Organic Framework with Asymmetric Dual-Function Hybrid Linkages for Promoting HO Photosynthesis in Air and Water.

Efficient sacrificial-agent-free photosynthesis of HO from air and water represents the greenest, lowest-cost, most real-time avenue for HO production but remains a challenging issue. Here, we show a general and effective approach through a structural design on covalent organic frameworks (COFs) with asymmetric dual-function hybrid linkages for boosting the HO photosynthesis of the COFs. Through such design we can equip a COF with not only a catalytic active center but also a special function for isolating the D-A motif, which consequently endows the COF (CI-COF) built on asymmetric dual-function hybrid linkages with a significantly enhanced efficiency in the generation, transmission, and separation of photogenerated carriers, relative to the COF (II-COF and CC-COF) built on symmetric single-function single linkages.

Ultrasound-activated erythrocyte membrane-camouflaged Pt (II) layered double hydroxide enhances PD-1 inhibitor efficacy in triple-negative breast cancer through cGAS-STING pathway-mediated immunogenic cell death.

Immunogenic cell death (ICD) offers a promising avenue for the treatment of triple-negative breast cancer (TNBC). However, optimizing immune responses remains a formidable challenge. This study presents the design of RBCm@Pt-CoNi layered double hydroxide (RmPLH), an innovative sonosensitizer for sonodynamic therapy (SDT), aimed at enhancing the efficacy of programmed cell death protein 1 (PD-1) inhibitors by inducing robust ICD responses.