Publications by authors named "F L Greenway"
The endocrine consequences of weight loss by bariatric surgery (BS) and caloric restriction are not fully understood but contribute to variable improvements in insulin sensitivity and cardiometabolic health. This study compared changes in insulin sensitivity and plasma concentrations of gut peptides 8 weeks and 1 year after BS and a low-calorie diet (LCD). Nineteen female patients with obesity self-selected BS (gastric bypass [n = 5] or sleeve gastrectomy [n = 7]) or LCD (n = 7) in this parallel-arm, prospective observational study.
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- Subjects with obesity have shown the ability to survive prolonged fasting, suggesting that ketone bodies play a crucial metabolic role beyond just glucose use.
- Early research on starvation revealed important insights into macronutrient metabolism and how the body adapts to ketosis, although prolonged fasting is no longer considered a treatment for obesity.
- Intermittent fasting and approaches like time-restricted eating are less extreme alternatives that still offer metabolic benefits, but the exact mechanisms behind these changes are not yet fully understood.
Article Synopsis
- - The EXACT trial, sponsored by the National Cancer Institute, aims to evaluate whether 150 minutes of weekly moderate-intensity aerobic exercise can lower systemic inflammation in stage I-III colorectal cancer survivors compared to a control group over 12 weeks.
- - Recruitment for the study involved inviting over 3,000 survivors, with 89 screened and 60 randomized, revealing that younger age, female sex, and certain racial and clinical factors positively influenced participation.
- - Findings showed high exercise adherence at 92.2%, with all participants meeting the 80% adherence goal, and the trial will provide insights into how exercise may help prevent cancer recurrence and improve survival rates.
Excess adiposity is at the root of type 2 diabetes (T2D). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as first-line treatments for T2D based on significant weight loss results. The composition of weight loss using most diets consists of <25% fat-free mass (FFM) loss, with the remainder from fat stores.
View Article and Find Full Text PDFBackground: mHealth interventions use mobile and wireless technologies to deliver aspects of healthcare, and have been extensively employed in mental health research, showcasing their potential to address the significant treatment gap. While numerous studies underscore the advantages and functionalities of mHealth, challenges persist regarding patient uptake and sustained engagement among individuals with psychosis spectrum disorder. This review aims to explore individual-level barriers and facilitators to engagement with hybrid digital systems, which involves the integration of digital tools alongside in-person care.
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