Chick Chorioallantoic membrane (CAM) as an in-vivo model for the study of angiogenesis and lymphangiogenesis.

The high incidence of vascular and lymphatic metastasis is closely associated with poor prognosis and mortality in cancer. Finding effective inhibitors to prevent pathological angiogenesis and lymphangiogenesis relies on appropriate in-vivo models. The chick embryo chorioallantoic membrane (CAM) is a membrane formed by the fusion of the chorion and allantois during embryonic development.

Tissue-engineered cellulose tubes for microvascular and lymphatic reconstruction: A translational and feasibility study.

Background: Lymphedema microsurgery is an emerging treatment modality, with dissimilar long-term outcomes. One of the main technical challenges in lymphatic microsurgery is the identification and availability of suitable donor vessels for anastomosis. Tissue engineering using biomaterials has demonstrated promise in addressing vessel quality issues in other fields, but its application in microsurgery is still limited.

Bronze age Northern Eurasian genetics in the context of development of metallurgy and Siberian ancestry.

The Eurasian Bronze Age (BA) has been described as a period of substantial human migrations, the emergence of pastoralism, horse domestication, and development of metallurgy. This study focuses on two north Eurasian sites sharing Siberian genetic ancestry. One of the sites, Rostovka, is associated with the Seima-Turbino (ST) phenomenon (~2200-1900 BCE) that is characterized by elaborate metallurgical objects found throughout Northern Eurasia.

Lymphedema-Associated Fibroblasts Are Related to Fibrosis and Stage Progression in Patients and a Murine Microsurgical Model.

Background: The driver of secondary lymphedema (SL) progression is chronic inflammation, which promotes fibrosis. Despite advances in preclinical research, a specific effector cell subpopulation as a biomarker for therapy response or stage progression is still missing for SL.

Methods: Whole skin samples of 35 murine subjects of a microsurgically induced SL model and 12 patients with SL were collected and their fibroblasts were isolated.

Archaeology and social justice in island worlds.

Ongoing discussions about the problems of white supremacy and colonialism in archaeology are useful but have not, thus far, fully considered the exacerbated effects of these issues on small islands. In this opinion piece, we, two white women academics from the Global North with extensive experience working in the Dutch Caribbean and the Hawaiian Islands, observe these exacerbated effects in governance, academic hegemony, and community relations, and call for more consideration of the effects of our discipline in small island contexts. Ultimately, in line with the observations of local, descendant, and Indigenous scholars, we argue that archaeologists must invest in de-colonial, antiracist, and social justice efforts in heritage fields and industries by foregrounding the wishes and needs of island communities.