Publications by authors named "F L Abdullahi"

Background: Pneumococcal infections are associated with significant morbidity and mortality, especially at the extremes of age and in those with underlying conditions. Little is known about the risks, presentations or outcomes of invasive pneumococcal disease (IPD) during pregnancy or the postpartum period.

Methods: The UK Health Security Agency conducts enhanced national surveillance of IPD in England.

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  • HELLP syndrome is a serious health issue for pregnant women that can happen with conditions like preeclampsia, especially in places like Uganda where hospitals might not have all the necessary tests.
  • A study at Mbarara Regional Referral Hospital found that about 19% of pregnant women with preeclampsia or eclampsia had HELLP syndrome.
  • Younger mothers, those with stomach pain, and those coming from smaller health facilities were more likely to have HELLP syndrome.
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  • The UK shifted to a 1+1 infant immunization schedule for the PCV13 vaccine starting January 1, 2020, and a study analyzed its impact on invasive pneumococcal disease (IPD) in children aged 0-3 years.
  • A comparison was made between a birth cohort eligible for the new 1+1 schedule and historical cohorts under the previous 2+1 schedule, examining various metrics like incidence rates and clinical outcomes.
  • Findings showed no significant differences in IPD incidence, disease characteristics, or outcomes between the 1+1 and 2+1 cohorts after three years, indicating the new schedule did not adversely affect health outcomes in eligible children.
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  • Haemophilus influenzae serotype b (Hib) conjugate vaccines have decreased Hib disease globally, but some European countries are seeing a rise in invasive cases, prompting a study in England to analyze trends over 11 years.
  • The UK Health Security Agency conducted national surveillance, reporting 6881 invasive infections from 2012 to 2023, with 2% being Hib cases, primarily affecting adults (median age 51) and leading to bacteraemic pneumonia in most instances.
  • The study concluded that while invasive Hib disease remains rare in England, it primarily impacts adults with pre-existing conditions, with a low case-fatality rate and no significant increase in overall incidence.
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Background: In the conjugate vaccine era, viruses are the most common cause of meningitis. Here, we evaluated epidemiological trends in laboratory-confirmed viral meningitis across all age-groups over an 11-year period in England.

Methods: In England, hospital laboratories routinely report laboratory-confirmed infections electronically to the UK Health Security Agency.

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