[Menarche in Bulgarian--secular trend in twenty century].

Unlabelled: The aim of the study was to determine the time of menarche in Bulgarian girls and specify the changes in menarcheal age during 20 century.

Material And Methods: We examined in a longitudinal study 93 girls from 3 schools in Sofia in the period from 1994-2000.

Results: Mean age of menarche in girls was 11.

[Sperm disorder in males with obesity and metabolic syndrome--pilot study].

Unlabelled: The aim of the study was to compare the semen quality in men with metabolic syndrome /MS/ and controls.

Materials And Methods: Semen samples were collected from 42 males (mean age--27.69 +/- 7.

[The anti-mullerian hormone--physiology and application into clinical practice].

The Anti-Mullerian hormone /AMH/ is a glycoprotein of the transforming growth factor-beta superfamily. It induces regression of the Mullerian ducts during the male sex differentiation. The hormone actions occur through serin/threonin kinase receptors-AMHRI and AMHRII.

[Multiple pregnancy and microelements: zinc (preliminary report)].

The aim af the study was to define the concentration of zinc in sera of women with multiple pregnancies during the last trimester and to compare it with the values in normal pregnancies. The study included 12 women with gemini and 67 with single fetus pregnancies. A statistically significant decrease was found in the mean zinc concentration in twin pregnancies--8.

[The copper concentration in the maternal serum in missed abortion].

Two groups of women with missed abortion examined in different periods of time were included in the study--the first group of 43 patients was examined in 1989-1990 and the second group of 24 in 1994. The control group consist of 73 women in the first trimester of normal pregnancy and 75 nonpregnant women. The serum copper concentration of the first group with missed abortion (19.